Clara Cell Protein (Club Cell Protein) is a New Diagnostic Molecular Candidate Biomarker in Nosocomial Pneumonia
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چکیده
منابع مشابه
Clara cell protein in bronchoalveolar lavage fluid: a predictor of ventilator-associated pneumonia?
INTRODUCTION Clara cell protein 10 (CC-10) has been associated with inflammatory and infectious pulmonary diseases. This study evaluates CC-10 concentrations in bronchoalveolar lavage (BAL) fluid as a potential marker of ventilator-associated pneumonia (VAP). METHODS Between January 2003 and December 2007, BAL fluid samples obtained from critically ill patients at the intensive care unit of t...
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Exposure to ozone (O3) impairs lung function, induces airway inflammation and alters epithelial permeability. Whilst impaired lung function and neutrophilia have been observed at relatively low concentrations, altered lung epithelial permeability is only seen after high-dose challenges. The appearance of Clara cell protein (CC16) in serum has been proposed as a sensitive marker of lung epitheli...
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The 16 kDa Clara cell protein (CC16), an abundant component of airway secretions, has recently been proposed in humans as a pulmonary marker measurable not only in bronchoalveolar lavage fluid (BALF) but also in serum. The aim of the present study was to investigate the changes and determinants of CC16 concentrations in these fluids in normal rats and rats with lung injury. Female Sprague-Dawle...
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Clara cells represent the predominant secretory cell within distal conducting airways of mammals and exhibit functional alterations with chronic lung disease. We previously demonstrated that Clara cell secretory protein (CCSP) deficiency results in enhanced susceptibility to environmental agents. The present study was undertaken to define changes in Clara cell secretory function associated with...
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ژورنال
عنوان ژورنال: General Reanimatology
سال: 2014
ISSN: 1813-9779
DOI: 10.15360/1813-9779-2014-6-6-14